Non-infectious pediatric uveitis in a single french tertiary center

Results Of 32 children included there were 62 % of females and the mean age at diagnosis was 7.7 ± 3.4 years and 6.5 ± 3.8 years for JIAU. Ophthalmologic complications were present at the diagnosis in 72% of patients. Uveitis was unilateral in 56 % of cases and anterior in 75 % of cases. At the time of the last follow-up 41% were idiopathic uveitis and 41% JIAU. The number of inflammatory cells in the uvea (Tyndall) was improved in 50 % of cases and stabilized in 50 % of cases. One third of patients had presented new ophthalmologic complications. Uveitis was recurrent in 84 % of cases and 75% of uveitis had relapsed at least once. Local corticosteroid was always used in combination with systemic treatment . Corticotherapy was used in 41% of cases, and associated to DMARDS (methotrexate) in 19% of patients. Anti-TNFa (adalimumab) was used in 42% of patients and 54% of JIAU. An improvement in the visual acuity of our cohort was found (4/10 initially versus 6.3/10). In the subgroup of JIAU (13 patients) visual acuity was modified from 4/ 10 to 5/10 and 23% patients used the systemic association;corticosteroid and methotrexate , 3 patients relapsed under adalimumab.